I loved NetHack back in the day. I think I'm strange in that I've always preferred the ASCII version to the graphical remakes over the years. I think you've done really well, but I find the controls a bit cumbersome.
I found it a bit tedious having to switch to Pickup all the time. I would like a setting so that items are automatically picked up when I walk over them. I'd also like an action to see my Inventory instead of going via wear / wield etc.
I also don't really see any value in the 4 boxes showing what I'm wielding or wearing - especially as they're not functional. For example, if I'm wielding a bow I still have to click Action then Fire to shoot it, instead of clicking on the Bow icon.
It would be really good if we could assign our own uses for the squares. i.e. I'd like to assign Pickup (if I can't have auto-Pickup), Search, Open, and Inventory. If I can have auto-Pickup then I would assign Fire. But hey, why not let each person customise what goes into each slot?