I'm having almost no issues running 14322 on my AT&T Lumia 640 GoPhone. I have tried to duplicate most of the bugs others have mentioned, and I a happy to say I have been unsuccessful at reproducing any of them. Bugs I have not tried to duplicate are the ones that do not apply to me, like anything with Band 2 connectivity, since I don't own a wearable device at all, and I have not tested issues with Messenger, because I don't use it or even have it installed.
I did have an issue with Quiet Hours not turning on and off per schedule at first, but turning it off manually, then back on and resetting the auto times fixed that issue.
I do have an issue with decreased battery life. It has to be charged mid-day with mild usage. It gets short, quick charges throughout the day now. It's not much of a hassle for me, since I'm at home (retired and raising children) most of the time. When I'm out and about, it gets plugged into the car charger, which is Quick Charge 2.0 compliant, and it stays at a good charge level for me most of the time. While at home, I do have available chargers plugged in at pretty much every room of the house, so I have no issues there either.
Loving 14322 so much, that I can tolerate the battery issues. Looking forward to things getting even better as we get close to a summer-time release of the Anniversary Update. I think they'll be ready for it in time.