I've been using the CS6 suite on mine since day 1. It is no where in the same league as my Alienware 18x (16GB 1866mhz RAM, overclocked i7Xtreme, dual Radeon 6970 crossfire, dual 512GB SSDs), but actually runs better than my Alienware 11x (SB i7 1.7ghz, 256GB SSD, Nvidia 335m, 8GB RAM).
I have been able to run Photoshop 64, After Effects, Premier, and Audition. I actually captured a very high quality 250MB audio file walking around with a Sennheiser shotgun boom mic directly into Audtion, captured a second file, and mixed right on the spot. Very nice.