I know you want a yes/no answer, but the thing is, what is acceptable for you may not be for someone else and vice versa.
Production 10586 builds are almost unacceptable for me for the odd quirks but plenty enjoy it. If you can afford to hard reset your device, I'd say feel free to do it. But if you cannot risk ANY downtime, then don't rock the boat. (which means don't do it)