ESET NOD32 Antivirus stops zero-day threats, but does have some setbacks.

[Windows Central]

Stops new threats quickly, even if they aren't yet in all the virus databases.
ESET NOD32 Antivirus stopped most of the threats we used during our tests of this software, and it is especially good at identifying new threats that haven't yet been added to malware databases. We didn't experience any lag on our computers while scans were performing, including when deep virus scans and system scans were running at the same time. This makes ESET a good antivirus software choice.

Full story from the WindowsCentral blog...