just forget about it for the moment, if you enable autoupload it sends ALL your photos to onedrive, ALL OF THEM, no matter what, if you have taken like 3000 pics since 8.1 your app will simply hang with a non-ending list of uploads failing, from time to time you will see 2 year old photos appearing on your pc, quite the nightmare right... if you disable autoupload and then enable it after a few minutes it will upload any photo you take easily for a while, then it will start uploading everything again and then nothing you shoot will get through since it is being put at the end of the queue
now if you want to upload manually and it fails too(its w10, what were you expecting?) you can reset the app, there's a setting hidden somewhere and then it will work again for manual uploads