I've been running all builds since preview launched on all my daily drivers (PC, laptop, tablet), and the only real issues arose on my tablet. Apart from that there have been some bugs, but none of them where unbearable for my usage. That said, build 10162 feels like a complete build to me, minus some refinement issues.
I've had the last several builds on my Surface Pro 2, which is my only 'laptop' type device and I use it every day with, for the most part, no issues. I do not yet have Windows 10 in any form on my gaming PC, but that is because I dont want to deal with redoing things every time a new build comes out.