Mouse not working

I downloaded windows 10 yesterday. Now the buttons below the mouse pad don't work. Initially the mouse didn't work,but I was able to find the setting for it and fix it. I'm able to move the cursor but can't select anything with the button or by tapping the mouse. I have a Bluetooth mouse and it works ok. Anyone know where the settings are for the buttons on the bottom? I have a Toshiba laptop. Thank you.

Also my laptop does not have a touch screen.

The only way I can scroll via my mouse pad is after I've done a restart. Worked fine in W7. So long as I keep the laptop switched on, after a restart, it works fine in W10.

I have a Lenovo 570 laptop.